This Unexpected Asthma Drug May Help Food Allergy

Omalizumab, a medication commonly used to treat asthma drug, may provide relief for individuals with multiple food allergies. A new clinical trial found the drug significantly reduced allergic reactions in many patients who accidentally consumed foods like peanuts and eggs they were allergic to.

The study involved 180 participants between ages 1-55 who had allergies to peanuts as well as 2 or more other common foods like cashews, milk, eggs, walnuts, wheat and hazelnuts. Half received omalizumab injections while the other half received a placebo. After 16 weeks, over 66% of those receiving the asthma drug could tolerate 600mg of peanut protein or more without serious symptoms, compared to just 6.8% on placebo.

How Does an Asthma Drug Help With Food Allergies?

Omalizumab works by binding to IgE antibodies, preventing them from attaching to immune cells and triggering an allergic reaction. For food allergies, this means the asthma drug essentially “turns down the volume” of the allergic response. While not a cure, it provides a layer of protection that could make a big difference for accidental exposures.

Most participants saw increased tolerance for multiple foods. After continuing treatment for 24 additional weeks, thresholds remained stable or increased further. The results suggest this asthma drug may give food allergy sufferers, especially those with multiple allergies, a new level of freedom and peace of mind. Larger and more diverse trials will provide more insight into who benefits most. But for many, omalizumab could be a game-changer.